In order to be enrolled in a clinical trial at the ALS Center you must be able to visit the ALS Center as determined by the clinical trial protocol.
If you are able to be evaluated at the Center and are interested in participating in a trial, please contact Kate Dalton, MS, RD at alscenter@columbia.edu or 212-305-2027.
General inquiries regarding clinical trials and results from clinical trials cannot be obtained at the Center.
| STUDY |
SPONSOR |
ENROLLMENT STATUS |
| Clinical Trial of Ceftriaxone in Subjects with ALS |
National Institute of Health |
Enrolling
Description of study |
| Prospective, Metropolitan New York, Community-based, Case-controlled, Ambispective Study of Oxidative Stress in Patients with Sporadic ALS |
National Institute of Health |
Enrolling
Description of study |
| Non-Invasive Ventilation in ALS |
Wings Over Wallstreet, ALSA, Stony Wald-Herbert foundation |
Enrolling
Description of study |
| A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Assess the Efficacy, Tolerability and Safety of Talampanel in Subjects with ALS |
Teva Pharmaceuticals |
Enrollment completed;
Data analysis ongoing
Description of study |
| A Double-Blind, Randomized, Placebo-Controlled, Multicenter Study to Assess the Safety and Efficacy, and to Determine the Pharmacokinetics of Two Doses of AVP-923 (Dextromethorphan/Quinidine) in the Treatment of Pseudobulbar Affect (PBA) in Patients with Amyotrophic Lateral Sclerosis and Multiple Sclerosis |
Avanir Pharmaceuticals |
Enrollment completed;
Data analysis ongoing
Description of study |
| A Multicenter, Double-Blind, Placebo-Controlled, Study to Investigate the Safety and Efficacy of Lithium in combination with Riluzole in ALS |
National Institute of Health, ALS Association, ALS Society of Canada |
Enrollment completed;
Data analysis ongoing
Description of study |
| A 2-Part, Randomized, Double-Blind, Safety and Tolerability Study Evaluating KNS-760704 in Patients with Amyotrophic Lateral Sclerosis (ALS) |
Knopp Neurosciences |
Enrollment completed;
Data collection ongoing
Description of Study |
| Excercise and Oxidative Stress in ALS |
National Institute of Health |
Enrollment completed;
Data analysis ongoing
Description of study |
| Efficacy of Using Cutometer Measurements as a Biomarker for the Progression of ALS |
ArbesIdeas |
Enrollment completed;
Data collection ongoing
Description of study |
| ALS Research Group DNA Banking Longitudinal Data Collection |
National Institute of Health, Muscular Dystrophy Association, ALS Association |
Enrollment completed;
Data collection ongoing
Description of study |
| ALS Genetic and Environmental Epidemiology |
Muscular Dystrophy Association |
Enrollment completed;
Data analysis ongoing
Description of study |
| Cognitive Function in ALS |
Wings over Wall Street, National Institute of Health |
Enrollment completed;
Data analysis ongoing |
| Modafinal for Fatigue in ALS |
Research Foundation for Mental Hygiene |
Enrollment completed;
Data analysis ongoing |
| Early Treatment of ALS With Nutrition and NIPPV |
National Institutes of Health |
Enrollment completed;
Data analysis ongoing |
| Clincial Trial of High Dose CoQ10 in ALS |
National Institutes of Health |
MS published |
| Combination Therapy Selection Trial |
ALS Association
Wings Over Wall Street (MDA)
Ride for Life |
MS published |
| Copaxone in ALS |
Independently Funded |
MS published |
| Diagnostic and Natural History Markers in Amyotrophic Lateral Sclerosis |
National Institutes of Health |
MS published |
| Improved Palliative and End-of-life Care |
National Institutes of Mental Health |
MS published |
| Minocycline in ALS |
National Institutes of Health |
MS published |
| Aeolus 10150 |
Aeolus Pharmaceuticals |
Enrollment completed |
| Aeolus 10150 – A multiple Dose Study |
Aeolus Pharmaceuticals |
Enrollment completed |
| Skin Biopsies for Generation of ALS- Specific Human Embryonic Stem Cells |
Project ALS |
Enrollment open for SOD-1 patients only;
Data analysis ongoing
Description of study |
